20.04.1938
Private Clinic in Psychiatry with 40 beds under the direction of Dr. Ljuben Russev and Dr. Russeva. Prof. Dr. Nikola Shipkovenski - supervisor of doctors calls.
For the first time in Bulgaria an electroconvulsive therapy has been applied.

1949 - 1951
Department in psychiatry in "Queen Giovanna" University hospital with 70 beds.
Department director: Prof. Dr. Trajko Zaprjanov

01.01.1951
Scientific institute in psychoneurology.
Department in neurology with 50 beds and department in psychiatry with 70 beds in "Queen Giovanna" University hospital.
For the first time in Bulgaria Dr. Dimitrov has introduced the insulin-comatose therapy.
Department directors: Prof. Dr. E. Sharankov and Prof. Dr. G. Nastev

1956
Scientific institute in neurology and psychiatry.
Department in neurology with 50 beds and deprtment in psychiatry with 70 beds in "Queen Giovanna" University hospital.
Prof. Dr.W. Ivanov has introduced the sleep therapy.
Department director: Prof. Dr. G. Ganev

1960
An own sector in neurology with 140 beds devided in 4 departments. An own sector in psychiatry divided in 2 departments - the first sector with 70 beds and the second with 256 beds.
Department in neurosurgery until 1973.
Executive director: Prof. Dr. G. Ganev.

1972
Sectors in neurology, psychiatry and neurosurgery.
Executive director: Prof. Dr. G. Ganev.

1976
Scientific institute in neurology, psychiatry and neurosurgery.
Department in neurology with 156 beds and department in psychiatry with 170 beds.
Executive directors: Prof. Dr. I. Georgiev, Prof. Dr. H. Hristosov, Prof. Dr. Ivanov,
Prof. Dr. Karkeseljan and Prof. Dr. Milanov.

1992
Public university hospital in neurology and psychiatry with 5 departments and 242 beds.
Executive directors: Assoc. Prof. Boeva and Assoc. Prof. Veltsheva

2000
Specialized university hospital for active treatment in neurology and psychiatry "Saint naum" with 9 clinics and departments in physical therapy, rehabilitation and reflexotherapy with 230 beds.
Executive director: Prof. Dr. Ivan Milanov, MD, PhD, DSc

2005
Conferment of Certificate № Q 050406 EN ISO 9001 : for introduction and execution of the System for management of quality in the following areas: diagnostic, treatment and rehabilitation, prevention, consultative activity, experts proceedings, training of students, postgraduate students and physicians in training, scientific research, development of new diagnostic and therapeutic methods.